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Is Sugar Killing Us?

Monday, April 2nd, 2012

If you are what you eat, then what does it mean that the average American consumes 130 pounds of sugar a year? Sanjay Gupta reports on new research showing that beyond weight gain, sugar can take a serious toll on your health, worsening conditions ranging from heart disease to cancer. Some physicians go so far as to call sugar a toxin.

The following script is from “Sugar” which aired on April 1, 2012. Dr. Sanjay Gupta is the correspondent. Denise Schrier Cetta and Sumi Aggarwal, producers

The chances are good that sugar is a bigger part of your daily diet than you may realize which is why our story tonight is so important. New research coming out of some of America’s most respected institutions is starting to find that sugar, the way many people are eating it today, is a toxin and could be a driving force behind some of this country’s leading killers, including heart disease.

As a result of these findings, an anti-sugar campaign has sprung up, led by Dr. Robert Lustig, a California endocrinologist, who believes the consumption of added sugars has plunged America into a public health crisis.

Dr. Sanjay Gupta: Is sugar toxic?

Dr. Robert Lustig: I believe it is.

Dr. Sanjay Gupta: Do you ever worry that that’s– it just sounds a little bit over the top?

Dr. Robert Lustig: Sure. All the time. But it’s the truth.

Dr. Robert Lustig is a pediatric endocrinologist at the University of California, San Francisco and a pioneer in what is becoming a war against sugar.

Motivated by his own patients — too many sick and obese children – Dr. Lustig has concluded that sugar, more than any other substance, is to blame.

Dr. Sanjay Gupta: What are all these various diseases that you say are linked to sugar?

Dr. Robert Lustig: Obesity, type II diabetes, hypertension, and heart disease itself.

Lustig says the American lifestyle is killing us.

Dr. Sanjay Gupta: And most of it you say is preventable?

Dr. Robert Lustig: Seventy-five percent of it is preventable.

While Dr. Lustig has published a dozen scientific articles on the evils of sugar, it was his lecture on YouTube, called “Sugar: The Bitter Truth,” that brought his message to the masses.

By “bad food” Dr. Lustig means the obvious things such as table sugar, honey, syrup, sugary drinks and desserts, but also just about every processed food you can imagine, where sugar is often hidden: yogurts and sauces, bread, and even peanut butter. And what about the man-made, often vilified sweetener, high fructose corn syrup?

Dr. Sanjay Gupta: Is it worse than just table sugar?

Dr. Robert Lustig: No. ‘Cause it’s the exact same. They are basically equivalent. The problem is they’re both bad. They’re both equally toxic.

Since the 1970s, sugar consumption has gone down nearly 40 percent, but high fructose corn syrup has more than made up the difference. Dr. Lustig says they are both toxic because they both contain fructose — that’s what makes them sweet and irresistible.

Dr. Robert Lustig: We love it. We go out of our way to find it. I think one of the reasons evolutionarily is because there is no food stuff on the planet that has fructose that is poisonous to you. It is all good. So when you taste something that’s sweet, it’s an evolutionary Darwinian signal that this is a safe food. Click to continue »

Cancer Cells Thrive On High Fructose Corn Syrup

Wednesday, August 4th, 2010

* Study shows fructose used differently from glucose

* Findings challenge common wisdom about sugars

Pancreatic tumor cells use fructose to divide and proliferate, U.S. researchers said on Monday in a study that challenges the common wisdom that all sugars are the same.

Tumor cells fed both glucose and fructose used the two sugars in two different ways, the team at the University of California Los Angeles found.

They said their finding, published in the journal Cancer Research, may help explain other studies that have linked fructose intake with pancreatic cancer, one of the deadliest cancer types.

“These findings show that cancer cells can readily metabolize fructose to increase proliferation,” Dr. Anthony Heaney of UCLA’s Jonsson Cancer Center and colleagues wrote.

“They have major significance for cancer patients given dietary refined fructose consumption, and indicate that efforts to reduce refined fructose intake or inhibit fructose-mediated actions may disrupt cancer growth.”

Americans take in large amounts of fructose, mainly in high fructose corn syrup, a mix of fructose and glucose that is used in soft drinks, bread and a range of other foods.

Politicians, regulators, health experts and the industry have debated whether high fructose corn syrup and other ingredients have been helping make Americans fatter and less healthy.

Too much sugar of any kind not only adds pounds, but is also a key culprit in diabetes, heart disease and stroke, according to the American Heart Association.

Several states, including New York and California, have weighed a tax on sweetened soft drinks to defray the cost of treating obesity-related diseases such as heart disease, diabetes and cancer.

The American Beverage Association, whose members include Coca-Cola (KO.N) and Kraft Foods (KFT.N) have strongly, and successfully, opposed efforts to tax soda. [ID:nN12233126]

The industry has also argued that sugar is sugar.

Heaney said his team found otherwise. They grew pancreatic cancer cells in lab dishes and fed them both glucose and fructose.

Tumor cells thrive on sugar but they used the fructose to proliferate. “Importantly, fructose and glucose metabolism are quite different,” Heaney’s team wrote.

“I think this paper has a lot of public health implications. Hopefully, at the federal level there will be some effort to step back on the amount of high fructose corn syrup in our diets,” Heaney said in a statement.

Now the team hopes to develop a drug that might stop tumor cells from making use of fructose.

U.S. consumption of high fructose corn syrup went up 1,000 percent between 1970 and 1990, researchers reported in 2004 in the American Journal of Clinical Nutrition.

Source: Reuters

High Fructose Corn Syrup vs. Sugar – Study Suggests They Are Not The Same?

Sunday, March 28th, 2010

You may already be aware of a new published study led by Princeton University researchers suggesting that high fructose corn syrup may play a more important role in the obesity epidemic than table sugar.

Bart Hoebel, who specialize in the neuroscience of appetite, found that of rats that drank the same amount of sugar and high fructose corn syrup (or HFCS), those that consumed the HFCS gained significantly more body weight than those drinking table sugar.

Furthermore, they found that drinking a HFCS solution for a long term, (which is the case of rats is six months), the rats experienced some signs of metabolic syndrome, such as abnormal increases in body fat and circulating blood fats called triglycerides.

This is an animal study. The results may not apply to humans; animals do not have the critical thinking skills to help them monitor their intake of sweeteners.

The Center for Consumer Freedom, the non-profit organization that often attacks research findings that may potentially hurt the food industry or the food service industry, issued a statement on March 26 claiming that “Every day, more people are pointing out flaws in last month’s Princeton University study finding that rats fed high fructose corn syrup gained more weight than rats fed sucrose.”

The Corn Refiners Association maintains that high fructose corn syrup is the same as table sugar nutritionally, and it launched a national TV campaign to educate consumers and extol the sweetener’s virtues, fooducate.com reported last year.

Some major food companies like PepsiCo have already decided to stop using high fructose corn syrup in their foods and beverages, due to the demand from food consumers for alternative sweeteners.

In 2007, Rutgers University researchers reported that high fructose corn syrup contains astonishingly high levels of reactive carbonyls, which can lead to oxidative damage of retinal proteins, according to Pennathur S and colleagues who published a study in the June 17, 2005 issue of Journal of Biological Chemistry addressing the potentially damaging effect of reactive carbonyls and polyunsaturated fattyacids on retinal proteins.